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Mutation Information
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Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV) |
Literature Information
|
PubMed PMID
|
15968338
|
|
Published Year
|
2005 |
|
Journal
|
International journal of medical sciences |
|
Title
|
Natural History and Clinical Consequences of Hepatitis B Virus Infection. |
|
Author
|
Pan CQ,Zhang JX |
|
Evidence
|
There are five clinically relevant HBV types: wild-type HBV, precore mutants, core promoter mutants, tyrosine-methionine-aspartate-aspartate (YMDD) mutants induced by lamivudine treatment, and asparagine to threonine (rtN236T) mutants recently identified in patients with adefovir treatment.
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