|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.N236T+rt.A181V |
|
Relevant Drug
|
adefovir (ADV) |
Literature Information
|
PubMed PMID
|
17692425
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
Journal of hepatology |
|
Title
|
Pooled analysis of amino acid changes in the HBV polymerase in patients from four major adefovir dipivoxil clinical trials. |
|
Author
|
Borroto-Esoda K,Miller MD,Arterburn S |
|
Evidence
|
BACKGROUND/AIMS: The rtA181V and rtN236T mutations have been associated with resistance to adefovir dipivoxil (ADV).
|
|
|
HBV Mutation Detail Information