|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
18329126
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2008 |
|
Journal
|
Journal of hepatology |
|
Title
|
Lamivudine compared with lamivudine and adefovir dipivoxil for the treatment of HBeAg-positive chronic hepatitis B. |
|
Author
|
Sung JJ,Lai JY,Zeuzem S,Chow WC,Heathcote EJ,Perrillo RP,Brosgart CL,Woessner MA,Scott SA,Gray DF,Gardner SD |
|
Evidence
|
At week 100, one patient in the combination group was found to have developed the N236T mutation (but not the M204V/I mutation)
|
|
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HBV Mutation Detail Information