|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM);telbivudine (LDT);adefovir dipivoxil (ADV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
24160943
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2013 |
|
Journal
|
Virology journal |
|
Title
|
Profile of hepatitis B virus resistance mutations against nucleoside/nucleotide analogue treatment in Chinese patients with chronic hepatitis B. |
|
Author
|
Lei J,Wang Y,Wang LL,Zhang SJ,Chen W,Bai ZG,Xu LY |
|
Evidence
|
Additionally, among LAM/LdT-based monotherapy, 50% of patients who (4/8) received ADV add-on also detected rtN236T mutations.
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