|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.N236T+rt.A181T |
|
Genotype/Subtype
|
B;C |
|
Relevant Drug
|
adefovir dipivoxil (ADV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
26612031
|
|
Disease
|
HBV infection
|
|
Published Year
|
2015 |
|
Journal
|
Scientific reports |
|
Title
|
Epidemiology study of HBV genotypes and antiviral drug resistance in multi-ethnic regions from Western China. |
|
Author
|
Zhang Q,Liao Y,Chen J,Cai B,Su Z,Ying B,Lu X,Tao C,Wang L |
|
Evidence
|
Besides, another ADV-associated resistant mutation rtN236T had a higher prevalence in genotype B than genotype C in ADV-resistant patients (66.7% vs. 13.0%, P < 0.001) (Supplementary Table S6). In ETV-resistant patients, no difference of mutation rates between genotype B and C was observed (Supplementary Table S7).
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HBV Mutation Detail Information