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Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B;C |
|
Relevant Drug
|
adefovir dipivoxil (ADV);tenofovir (TNF) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
29713126
|
|
Published Year
|
2018 |
|
Journal
|
World journal of gastroenterology |
|
Title
|
Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression. |
|
Author
|
Choi YM,Lee SY,Kim BJ |
|
Evidence
|
Our literature based pooled incidence data showed that of primary drug resistance mutations, M204I/V is the most frequently encountered in treatment-naïve patients[14,28,33] (5.89%), which was far more than the pooled mutation rate of rtA181T/V, rtS202C/G/I and rtN236T (incidence: 1.16%, 0.85% and 0.81%, respectively).
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HBV Mutation Detail Information