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Mutation Information
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Mutation Site
|
N248A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
26825915
|
|
Disease
|
HBV infection
|
|
Published Year
|
2016 |
|
Journal
|
Medicine |
|
Title
|
Dynamics of Genotypic Mutations of the Hepatitis B Virus Associated With Long-Term Entecavir Treatment Determined With Ultradeep Pyrosequencing: A Retrospective Observational Study. |
|
Author
|
Zhang XX,Li MR,Cao Y,Zhang RW,Zhang Y,Li F,Xi HL,Xu XY |
|
Evidence
|
Meanwhile, the rtA181T substitution rose from 2.17% to 64.15% by 2 years, and certain nonresistance mutations (rtN248A, rtI224 V, and rtS223A) had increased significantly.
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HBV Mutation Detail Information