|
Mutation Information
|
Mutation Site
|
N248H |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Amino acid_Mutation
|
A1758C |
|
Relevant Drug
|
tenofovir (TDF) |
|
Country
|
Pakistan |
Literature Information
|
PubMed PMID
|
30285571
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2018 |
|
Journal
|
Viral immunology |
|
Title
|
Predictors of Therapeutic Outcome to Nucleotide Reverse Transcriptase Inhibitor in Hepatitis B Patients. |
|
Author
|
Aziz M,Aziz H,Waheed Y,Gill ML |
|
Evidence
|
Another mutation rtN248H observed in E motif considered to have effect on DNA primer grip, which forms part of binding pocket.
|
|
|
HBV Mutation Detail Information