|
Mutation Information
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Mutation Site
|
N255D |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
RT1t49 |
Literature Information
|
PubMed PMID
|
33095511
|
|
Published Year
|
2021 |
|
Journal
|
Chembiochem : a European journal of chemical biology |
|
Title
|
Characterization of New DNA Aptamers for Anti-HIV-1 Reverse Transcriptase. |
|
Author
|
Ratanabunyong S,Aeksiri N,Yanaka S,Yagi-Utsumi M,Kato K,Choowongkomon K,Hannongbua S |
|
Evidence
|
This aptamer inhibited the WT HIV‐1 RT DNA polymerase function, however, the point mutations at N255D and N265D positions appeared which conferred resistance to the RT1t49.
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HIV Mutation Detail Information