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Mutation Information
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Mutation Site
|
N320K |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PreS2 |
Literature Information
|
PubMed PMID
|
24282423
|
|
Published Year
|
2013 |
|
Journal
|
Hepatitis monthly |
|
Title
|
The N-Glycosylation Modification of LHBs (Large Surface Proteins of HBV) Effects on Endoplasmic Reticulum Stress, Cell Proliferation and its Secretion. |
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Author
|
Liu W,Cao Y,Wang T,Xiang G,Lu J,Zhang J,Hou P |
|
Evidence
|
The secretion of LHBs was blocked by N320K mutation, which could induce an increase in G1 phase and inhibition of S phase, and inhibited mitotic entry.
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HBV Mutation Detail Information