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Mutation Information
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Mutation Site
|
N40S |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
S |
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Genotype/Subtype
|
D |
Literature Information
|
PubMed PMID
|
11481624
|
|
Disease
|
Fulminant hepatitis B
|
|
Published Year
|
2001 |
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Journal
|
Hepatology (Baltimore, Md.) |
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Title
|
A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis. |
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Author
|
Kalinina T,Riu A,Fischer L,Will H,Sterneck M |
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Evidence
|
In addition to the 7 common mutations of the mutant S-proteins, there are 3 substitutions (N40S, I86T, and Y134F)that were only present in 2 of the 3 variant genome sequences(Fig. 1)
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