HIV Mutation Detail Information

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Mutation Information

Mutation Site	N40V
Mutation Type	Amino acid level
Gene/Protein/Region Type	Rev

Literature Information

PubMed PMID	31923334
Published Year	2020
Journal	Journal of molecular recognition : JMR
Title	Altered-specificity mutants of the HIV Rev arginine-rich motif-RRE IIB interaction.
Author	Raad NG,Ghattas IR,Amano R,Watanabe N,Sakamoto T,Smith CA
Evidence	Here, isothermal titration calorimetry and gel shift assays show that the R35G‐N40V‐IIB interaction has high affinity and specificity in vitro and a larger unfavorable entropy change upon binding than that of wild‐type Rev ARM‐IIB.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation