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Mutation Information
|
Mutation Site
|
N462T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Env |
|
Viral Reference
|
U71182
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
31178836
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
Frontiers in microbiology |
|
Title
|
Characteristics of Envelope Genes in a Chinese Chronically HIV-1 Infected Patient With Broadly Neutralizing Activity. |
|
Author
|
Zhang D,Zou S,Hu Y,Hou J,Hu X,Ren L,Ma L,He X,Shao Y,Hong K |
|
Evidence
|
Almost all of Env clones presented a mutation N462T, and combined with N460 produced a PNGS, which may be a potential obstruction to the interaction between VRC01 and Env.
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