|
Mutation Information
|
Mutation Site
|
N74D |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
CA |
|
Relevant Drug
|
coumermycin-A1 (C-A1) |
Literature Information
|
PubMed PMID
|
27107820
|
|
Published Year
|
2016 |
|
Journal
|
Retrovirology |
|
Title
|
HIV-1 capsid is involved in post-nuclear entry steps. |
|
Author
|
Chen NY,Zhou L,Gane PJ,Opp S,Ball NJ,Nicastro G,Zufferey M,Buffone C,Luban J,Selwood D,Diaz-Griffero F,Taylor I,Fassati A |
|
Evidence
|
A105S and N74D capsid mutant viruses did not accumulate capsid in the nucleus, irrespective of C-A1 treatment.
|
|
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HIV Mutation Detail Information