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Mutation Information
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Mutation Site
|
N74D |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
CA |
Literature Information
|
PubMed PMID
|
31690677
|
|
Published Year
|
2019 |
|
Journal
|
mBio |
|
Title
|
Analysis of CA Content and CPSF6 Dependence of Early HIV-1 Replication Complexes in SupT1-R5 Cells. |
|
Author
|
Zila V,Müller TG,Laketa V,Müller B,Kräusslich HG |
|
Evidence
|
Detectable but moderate impairment of infectivity caused by CPSF6 depletion or disturbance of CA-CPSF6 interaction through CA mutation N74D had also been demonstrated in earlier studies on macrophages.
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HIV Mutation Detail Information