|
Mutation Information
|
Mutation Site
|
P120A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Viral Reference
|
V01460.1
|
Literature Information
|
PubMed PMID
|
19570861
|
|
Published Year
|
2009 |
|
Journal
|
Journal of virology |
|
Title
|
A function essential to viral entry underlies the hepatitis B virus "a" determinant. |
|
Author
|
Salisse J,Sureau C |
|
Evidence
|
When infectivity and antigenicity are used as criteria for the mutants characterization, three phenotypes can be distinguished: (i) the wt phenotype displaying alteration of neither infectivity nor the “a” determinant; (ii) the infectivity-deficient phenotype that conserves the “a” determinant (i.e., P105A, V106A, P108A, T118A, G119A, R122A, T123A, P142A, N146A, T148A, I150A, and W156A); and (iii) the phenotype deficient for both the “a” determinant and infectivity: I110A, P120A, K141A, and P153A.
|
|
|