|
Mutation Information
|
Mutation Site
|
P120T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Combined Mutation
|
s.I126N+s.P120T;s.A128V+s.P120T |
|
Immune Escape
|
Y |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
28300730
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2017 |
|
Journal
|
Antiviral therapy |
|
Title
|
The enrichment of HBV immune-escape mutations during nucleoside/nucleotide analogue therapy. |
|
Author
|
Shan M,Shen Z,Sun H,Zheng J,Zhang M |
|
Evidence
|
Except for the combination of sP120T+sA128V, other double combinations (n=11) were only detected in the NA treatment group, and nine of these combinations in the treatment group were detected in HBV variants without antiviral resistance mutations.
|
|
|