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Mutation Information
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Mutation Site
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P124A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Gag |
Literature Information
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PubMed PMID
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30327442
|
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Published Year
|
2018 |
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Journal
|
mBio |
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Title
|
Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation. |
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Author
|
Novikova M,Adams LJ,Fontana J,Gres AT,Balasubramaniam M,Winkler DC,Kudchodkar SB,Soheilian F,Sarafianos SG,Steven AC,Freed EO |
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Evidence
|
Moreover, residue Q176 in the P122A mutant assumed a conformation different from that seen with CA WT (Fig. 5C and D), while Q176 adopted the WT conformation in the P124A mutant, despite some flexibility (Fig. 5E).
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