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Mutation Information
|
Mutation Site
|
P135Q |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
C |
|
Amino acid_Mutation
|
C2304A |
|
Genotype/Subtype
|
B |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
24273041
|
|
Disease
|
HBV infection
|
|
Published Year
|
2014 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
The impact of hepatitis B virus precore/core gene carboxyl terminal mutations on viral biosynthesis and the host immune response. |
|
Author
|
Wu JF,Ni YH,Chen HL,Hsu HY,Chang MH |
|
Evidence
|
Results: The P135Q and G1896A were the most prevalent mutants before HBeAg seroconversion, acting as markers of HBeAg seroconversion (hazard ratios = 2.75 and 4.50; P = .01 and <.001, respectively).
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HBV Mutation Detail Information