|
Mutation Information
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Mutation Site
|
P145S |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
IN |
Literature Information
|
PubMed PMID
|
33712691
|
|
Published Year
|
2021 |
|
Journal
|
Communications biology |
|
Title
|
Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome. |
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Author
|
Pandey KK,Bera S,Shi K,Rau MJ,Oleru AV,Fitzpatrick JAJ,Engelman AN,Aihara H,Grandgenett DP |
|
Evidence
|
The P145S change in HIV-1 IN confers EVG resistance, and the corresponding Ser150 residue in RSV IN conferred natural resistance to EVG.
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HIV Mutation Detail Information