|
Mutation Information
|
Mutation Site
|
P196A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
29353073
|
|
Disease
|
HBV infection
|
|
Published Year
|
2018 |
|
Journal
|
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology |
|
Title
|
Serum HBV DNA plus RNA shows superiority in reflecting the activity of intrahepatic cccDNA in treatment-naïve HBV-infected individuals. |
|
Author
|
Huang H,Wang J,Li W,Chen R,Chen X,Zhang F,Xu D,Lu F |
|
Evidence
|
Moreover, high-frequency R193M and P196A mutations were found in the RT region of HBV polymerase leading to lower serum HBV DNA and higher serum HBV RNA levels in HBeAg-negative chronic HBV infection phase.
|
|
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HBV Mutation Detail Information