|
Mutation Information
|
Mutation Site
|
P432L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
L1 |
|
Genotype/Subtype
|
HPV53 |
|
Viral Reference
|
X74482
|
|
Immune Escape
|
Y |
Literature Information
|
PubMed PMID
|
22001139
|
|
Disease
|
Low grade squamous intraepithelial lesion
|
|
Published Year
|
2012 |
|
Journal
|
Virus research |
|
Title
|
Human papillomaviruses 53 and 66: clinical aspects and genetic analysis. |
|
Author
|
Cento V,Rahmatalla N,Ciccozzi M,Lo Presti A,Perno CF,Ciotti M |
|
Evidence
|
The novel L1 mutation P432L was statistically associated with L-SIL lesions (P=0.04) and its development reduced the L1 predicted antigenicity (up to -2.3 for Glu433).
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HPV Mutation Detail Information