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Mutation Information
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Mutation Site
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P63H |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PR |
Literature Information
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PubMed PMID
|
30051611
|
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Published Year
|
2018 |
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Journal
|
Molecular informatics |
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Title
|
Flap-site Fragment Restores Back Wild-type Behaviour in Resistant Form of HIV Protease. |
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Author
|
Luchi A,Angelina E,Bogado L,Forli S,Olson A,Peruchena N |
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Evidence
|
Heaslet et al. have obtained the crystal structures of three mutant forms of HIV-PR containing one (1X: V82A), three (3X: V82A, M46I, F53L) and six (6X: V82A, M46I, F53L, V77I, L24I, L63P) point mutations.
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