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Mutation Information
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Mutation Site
|
P69S |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Nef |
Literature Information
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PubMed PMID
|
22643973
|
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Published Year
|
2012 |
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Journal
|
Journal of molecular modeling |
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Title
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Validation of a novel secretion modification region (SMR) of HIV-1 Nef using cohort sequence analysis and molecular modeling. |
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Author
|
Campbell PE,Isayev O,Ali SA,Roth WW,Huang MB,Powell MD,Leszczynski J,Bond VC |
|
Evidence
|
Of these representative sequences, there were only three examples of amino acid substitutions in the SMR, with changes from Val-66 to Glycine (Italian Cohort), Pro-69 to Serine (US cohort) and Val-70 to Glycine (US cohort).
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HIV Mutation Detail Information