HBV Mutation Detail Information

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Mutation Information

Mutation Site	Q101R
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Combined Mutation	s.Q101R+s.R122P
Genotype/Subtype	D
Country	Italy

Literature Information

PubMed PMID	22086128
Disease	Occult HBV infection
Published Year	2012
Journal	Antiviral research
Title	Novel HBsAg markers tightly correlate with occult HBV infection and strongly affect HBsAg detection.
Author	Svicher V,Cento V,Bernassola M,Neumann-Fraune M,Van Hemert F,Chen M,Salpini R,Liu C,Longo R,Visca M,Romano S,Micheli V,Bertoli A,Gori C,Ceccherini-Silberstein F,Sarrecchia C,Andreoni M,Angelico M,Ursitti A,Spanò A,Zhang JM,Verheyen J,Cappiello G,Perno CF
Evidence	Mutants (obtained by site-directed mutagenesis) carrying T116N, T116N+S143L, R122P, R122P+Q101R, or R122P+S167L strongly decreased HBsAg-reactivity (54.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation