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Mutation Information
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Mutation Site
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Q112D |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
CA |
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Relevant Drug
|
IFN-beta |
Literature Information
|
PubMed PMID
|
31941344
|
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Published Year
|
2020 |
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Journal
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AIDS research and human retroviruses |
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Title
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The 4th and 112th Residues of Viral Capsid Cooperatively Modulate Capsid-CPSF6 Interactions of HIV-1. |
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Author
|
Saito A,Sultana T,Ode H,Nohata K,Samune Y,Nakayama EE,Iwatani Y,Shioda T |
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Evidence
|
We recently identified a Q4R mutation in CA after propagation of an interferon (IFN)-beta-hypersensitive CA mutant, RGDA/Q112D (H87R, A88G, P90D, P93A and Q112D) virus, in IFN-beta-treated cells.
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HIV Mutation Detail Information