|
Mutation Information
|
Mutation Site
|
Q129H |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
D |
|
Viral Reference
|
V01460.1
|
|
Country
|
Italy |
Literature Information
|
PubMed PMID
|
25542480
|
|
Disease
|
Acute hepatitis B
|
|
Published Year
|
2015 |
|
Journal
|
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology |
|
Title
|
Acute hepatitis B caused by a vaccine-escape HBV strain in vaccinated subject: sequence analysis and therapeutic strategy. |
|
Author
|
Luongo M,Critelli R,Grottola A,Gitto S,Bernabucci V,Bevini M,Vecchi C,Montagnani G,Villa E |
|
Evidence
|
Of all the substitutions found, Q129H, located in the "a" determinant region of HBsAg, can alter antigenicity, leading to mutants.
|
|
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HBV Mutation Detail Information