HIV Mutation Detail Information

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Mutation Information

Mutation Site	Q148H
Mutation Type	Amino acid level
Gene/Protein/Region Type	IN
Country	Italy

Literature Information

PubMed PMID	31518723
Disease	HIV infection/AIDS
Published Year	2020
Journal	Journal of global antimicrobial resistance
Title	Transmitted drug resistance mutations and trends of HIV-1 subtypes in treatment-naïve patients: A single-centre experience.
Author	Mazzuti L,Melengu T,Falasca F,Calabretto M,Cella E,Ciccozzi M,Mezzaroma I,Iaiani G,Spaziante M,d'Ettorre G,Fimiani C,Vullo V,Antonelli G,Turriziani O
Evidence	Transmitted INSTI mutations (Q148H and G140S) responsible for high-level resistance to raltegravir and elvitegravir and intermediate resistance to dolutegravir and bictegravir were found, for the first time, in two individuals.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation