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Mutation Information
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Mutation Site
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Q16R |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
S |
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Country
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China |
Literature Information
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PubMed PMID
|
31516090
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Disease
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Occult HBV infection
|
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Published Year
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2019 |
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Journal
|
Emerging microbes & infections |
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Title
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Occult HBV infection in Chinese blood donors: role of N-glycosylation mutations and amino acid substitutions in S protein transmembrane domains. |
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Author
|
Zhang L,Chang L,Laperche S,Ji H,Zhao J,Jiang X,Wang L,Candotti D |
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Evidence
|
However, mutation Q16R resulted in decreased HBsAg secretion compared to wt M88 (EC/IC ratio: 0.57 versus 1.2) whereas a significant increase in HBsAg secretion was observed in P38.II (EC/IC ratio: 31 versus 0.5).
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HBV Mutation Detail Information