|
Mutation Information
|
Mutation Site
|
Q171K |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
C |
|
Viral Reference
|
AAP79736;
X02763 |
Literature Information
|
PubMed PMID
|
18647234
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2008 |
|
Journal
|
Journal of viral hepatitis |
|
Title
|
Expression of hepatitis B virus nuclear core antigen in young cirrhotic patients is associated with an unfavourable long-term outcome. |
|
Author
|
Yeh CT,Tang JH,Hsu CW,Chen YC,Chang ML,Lin CY |
|
Evidence
|
Site-directed mutagenesis experiments demonstrated that both the Q171K and Q179K mutation enhanced nuclear localization of the core protein.
|
|
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HBV Mutation Detail Information