|
Mutation Information
|
Mutation Site
|
Q476H |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
AF282918.1
|
Literature Information
|
PubMed PMID
|
19812261
|
|
Published Year
|
2010 |
|
Journal
|
The Journal of general virology |
|
Title
|
Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication. |
|
Author
|
Wu C,Zhang X,Tian Y,Song J,Yang D,Roggendorf M,Lu M,Chen X |
|
Evidence
|
In this study, the substitutions sK122I, sT123N and sK160N in HBsAg led to the substitutions rtQ476H, rtN477K and rtI515L in the polymerase.
|
|
|
HBV Mutation Detail Information