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Mutation Information
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Mutation Site
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Q652F |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
Env |
Literature Information
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PubMed PMID
|
32098152
|
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Published Year
|
2020 |
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Journal
|
Viruses |
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Title
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Identification of HIV-1 Envelope Mutations that Enhance Entry Using Macaque CD4 and CCR5. |
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Author
|
Roop JI,Cassidy NA,Dingens AS,Bloom JD,Overbaugh J |
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Evidence
|
For example, CHR mutations Q653L and Q652F improved infection of 293Trhm cells 9- and 7-fold, respectively, whereas the most advantageous NHR mutation, I573L, improved infection 4-fold (Figure 3a).
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