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Mutation Information
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Mutation Site
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R119Q |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
HBZ |
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Amino acid_Mutation
|
C272T |
|
Viral Reference
|
J02029.1
|
|
Country
|
Brasil |
Literature Information
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PubMed PMID
|
33835501
|
|
Disease
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HTLV-1 associated myelopathy/tropical spastic paraparesis;
Adult T cell leukemia/lymphoma;
HTLV-1 associated infective dermatitis;
HTLV1 infection
|
|
Published Year
|
2021 |
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Journal
|
Journal of medical virology |
|
Title
|
Molecular characterization of HTLV-1 genomic region hbz from patients with different clinical conditions. |
|
Author
|
Cucco MS,de Moraes LEP,de Oliveira Andrade F,Khouri R,Galvão-Castro B,Araujo TH,de Almeida Rego FF,Gois LL,Barreto FK,Santos LA |
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Evidence
|
The characterization showed that the R119Q mutation seems to be related to HTLV-1 clinical conditions, since the frequency of this HBZ mutation is significantly different in the comparison between AC with HAM/TSP and ATLL.
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HTLV1 Mutation Detail Information