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Mutation Information
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Mutation Site
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R151C |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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C |
Literature Information
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PubMed PMID
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19327810
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Published Year
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2009 |
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Journal
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Virology |
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Title
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Chimeric constructs between two hepatitis B virus genomes confirm transcriptional impact of core promoter mutations and reveal multiple effects of core gene mutations. |
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Author
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Tsai A,Kawai S,Kwei K,Gewaily D,Hutter A,Tong DR,Li J,Wands JR,Tong S |
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Evidence
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This finding, together with the results of the mapping experiments, establishes that amino acid substitutions at the N-terminus of the 2A core protein (A36Tor G64V) reduce the stringency of virion secretion, whereas amino acid changes at the C-terminus of怀 ņ㧄뮝褐ක 褐ක 褐ක 怀 传෧ 耀짠쾋羄 風 風 哨෧
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