HBV Mutation Detail Information

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Mutation Information

Mutation Site	R154G
Mutation Type	Amino acid level
Gene/Protein/Region Type	C

Literature Information

PubMed PMID	25890025
Published Year	2015
Journal	Journal of nanobiotechnology
Title	Mutation of arginine residues to avoid non-specific cellular uptakes for hepatitis B virus core particles.
Author	Bin Mohamed Suffian IF,Nishimura Y,Morita K,Nakamura-Tsuruta S,Al-Jamal KT,Ishii J,Ogino C,Kondo A
Evidence	RESULTS: The mutated HBc particles in which R154 was replaced with glycine (G) residue (R154G) showed a drastic decrease in the ability to bind to the heparan sulphate proteoglycan and to avoid non-specific cellular uptake by several types of cancer cells.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation