|
Mutation Information
|
Mutation Site
|
R18K |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
CA |
Literature Information
|
PubMed PMID
|
33524070
|
|
Published Year
|
2021 |
|
Journal
|
PLoS pathogens |
|
Title
|
A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly. |
|
Author
|
Renner N,Mallery DL,Faysal KMR,Peng W,Jacques DA,Böcking T,James LC |
|
Evidence
|
Mutant R18K/K25R was substantially less infectious than either single mutant alone, suggesting that mutation while preserving charge at one site does not prevent function at the other (Fig 2C).
|
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HIV Mutation Detail Information