|
Mutation Information
|
Mutation Site
|
R452G |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gag |
|
Relevant Drug
|
PIs |
Literature Information
|
PubMed PMID
|
25253273
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2014 |
|
Journal
|
Retrovirology |
|
Title
|
HIV-1 Gag C-terminal amino acid substitutions emerging under selective pressure of protease inhibitors in patient populations infected with different HIV-1 subtypes. |
|
Author
|
Li G,Verheyen J,Theys K,Piampongsant S,Van Laethem K,Vandamme AM |
|
Evidence
|
Patients failing DRV/r-based regimens developed Gag substitution patterns P453Ins or T427P + R452G.
|
|
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HIV Mutation Detail Information