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Mutation Information
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Mutation Site
|
R557L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Env |
Literature Information
|
PubMed PMID
|
32098152
|
|
Published Year
|
2020 |
|
Journal
|
Viruses |
|
Title
|
Identification of HIV-1 Envelope Mutations that Enhance Entry Using Macaque CD4 and CCR5. |
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Author
|
Roop JI,Cassidy NA,Dingens AS,Bloom JD,Overbaugh J |
|
Evidence
|
Consistent with the DMS data, mutations R557L and K588L, which improved infection of 293Trhm cells, were mildly detrimental in the context of 293Thu infection.
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HIV Mutation Detail Information