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Mutation Information
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Mutation Site
|
R563Q |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
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Gp41 |
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Country
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Boston |
Literature Information
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PubMed PMID
|
32392227
|
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Disease
|
HIV infection/AIDS
|
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Published Year
|
2020 |
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Journal
|
PLoS pathogens |
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Title
|
Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein. |
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Author
|
Joshi VR,Newman RM,Pack ML,Power KA,Munro JB,Okawa K,Madani N,Sodroski JG,Schmidt AG,Allen TM |
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Evidence
|
As a control, we verified that neither the arginine-expressing Env NE1 (NE1 Q563R) nor the glutamine-expressing Env E1 (E1 R563Q) mutants exhibited increased infectivity in the presence of HIV-negative plasm.
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HIV Mutation Detail Information