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HIV Mutation Detail Information

> R77Q Search Result


Mutation Information
Mutation Site R77Q
Mutation Type Amino acid level
Gene/Protein/Region Type Vpr
Literature Information
PubMed PMID 18808682
Published Year 2008
Journal Retrovirology
Title Direct Vpr-Vpr interaction in cells monitored by two photon fluorescence correlation spectroscopy and fluorescence lifetime imaging.
Author Fritz JV,Didier P,Clamme JP,Schaub E,Muriaux D,Cabanne C,Morellet N,Bouaziz S,Darlix JL,Mély Y,de Rocquigny H
Evidence The Q3R and R77Q mutants were shown to be impaired in their proapoptotic activity and to be associated with long-term non-progressive HIV-1 infection while the R90K mutant failed to cause the G2/M cell arrest.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation