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Mutation Information
|
Mutation Site
|
R7A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Small T |
|
Viral Reference
|
KM359729.1
|
Literature Information
|
PubMed PMID
|
25631078
|
|
Published Year
|
2015 |
|
Journal
|
Journal of virology |
|
Title
|
Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen. |
|
Author
|
Kwun HJ,Shuda M,Camacho CJ,Gamper AM,Thant M,Chang Y,Moore PS |
|
Evidence
|
Four substitution mutations (R7, K118, K134, and L142) were found to inhibit PP3A Aα subunit binding despite abundant sT protein expression.
|
|
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MCV Mutation Detail Information