|
Mutation Information
|
Mutation Site
|
R80A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Vpr |
Literature Information
|
PubMed PMID
|
9874563
|
|
Published Year
|
1999 |
|
Journal
|
The Journal of experimental medicine |
|
Title
|
The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor. |
|
Author
|
Kino T,Gragerov A,Kopp JB,Stauber RH,Pavlakis GN,Chrousos GP |
|
Evidence
|
A second point mutant, VprR80A, showed the opposite phenotype;it had coactivation function similar to Vpr, but did not arrest cells in G2/M.
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HIV Mutation Detail Information