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Mutation Information
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Mutation Site
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R841I |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Env |
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Viral Reference
|
K03455.1
|
|
Country
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Canada |
Literature Information
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PubMed PMID
|
31683782
|
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Disease
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HIV infection/AIDS
|
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Published Year
|
2019 |
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Journal
|
Viruses |
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Title
|
HIV-1 Envelope Glycoprotein Amino Acids Signatures Associated with Clade B Transmitted/Founder and Recent Viruses. |
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Author
|
Kafando A,Martineau C,El-Far M,Fournier E,Doualla-Bell F,Serhir B,Kazienga A,Sangaré MN,Sylla M,Chamberland A,Charest H,Tremblay CL |
|
Evidence
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This mutation of R to I (R841I) in the gp41 cytoplasmic tail (gp41CT), specifically in lentivirus lytic peptides segment 1 (LLP-1), is significantly enriched compared to chronic viruses (OR = 0.2, 95% CI (0.09, 0.44), p = 0.00001).
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HIV Mutation Detail Information