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Mutation Information

Mutation Site	S109A
Mutation Type	Amino acid level
Gene/Protein/Region Type	CA

Literature Information

PubMed PMID	18605989
Published Year	2008
Journal	Retrovirology
Title	VSV-G pseudotyping rescues HIV-1 CA mutations that impair core assembly or stability.
Author	Brun S,Solignat M,Gay B,Bernard E,Chaloin L,Fenard D,Devaux C,Chazal N,Briant L
Evidence	Viruses were produced by transfection experiments of 293T cells with pNL4.3 or S109A, S149A and S178A mutated molecular clones and used to infect the MAGIC-5B indicator cell line (Figure 2A). All three mutants were found to be poorly infectious compared to the NL4.3 wild-type (WT) viruses when viral input was normalized according to reverse transcriptase (RTase) activity.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation