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Mutation Information
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Mutation Site
|
S11F |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PreC |
|
Country
|
Kyrgyzstan |
Literature Information
|
PubMed PMID
|
32155009
|
|
Disease
|
Hepatocellular carcinoma;
Liver cirrhosis;
Chronic hepatitis B
|
|
Published Year
|
2020 |
|
Journal
|
Klinicheskaia laboratornaia diagnostika |
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Title
|
[The prevalence clinically significant virus mutations among patients with chronic viral hepatitis B.] |
|
Author
|
Ostankova YV,Semenov AV,Zueva EB,Nogoybaeva KA,Kasymbekova KT,Tobokalova ST,Totolian AA |
|
Evidence
|
Another 12.5% of the isolates are characterized by mutations that are independently associated with theLiver cirrhosis and hepatocellular carcinoma development, including 21, 24, 27 nucleotides deletions in the Pre-S2 region and the S11F mutation in the PreCore region.
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