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Mutation Information
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Mutation Site
|
S130F |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreS2 |
|
Genotype/Subtype
|
D |
|
Viral Reference
|
X85254.1;
M32138.1;
FJ904433.1;
AF121240.1;
X65259.1 |
|
Country
|
Iran |
Literature Information
|
PubMed PMID
|
31501793
|
|
Disease
|
Liver cirrhosis
|
|
Published Year
|
2019 |
|
Journal
|
Clinical and experimental hepatology |
|
Title
|
Comparison of pre-S1/S2 variations of hepatitis B virus between asymptomatic carriers and cirrhotic/hepatocellular carcinoma-affected individuals. |
|
Author
|
Taghiabadi M,Hosseini SY,Gorzin AA,Taghavi SA,Monavari SHR,Sarvari J |
|
Evidence
|
Moreover, an S130F/L mutation in the pre-S2 region of the LC samples (22.22%; 2/9) and a substitution at the start codon of the pre-S2 (Met1R) region in 11.76% (2/17) of the HCC cases were also detected, with a non-significant difference (p = 0.46) (Fig. 1).
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HBV Mutation Detail Information