HBV Mutation Detail Information

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Mutation Information

Mutation Site	S142P
Mutation Type	Amino acid level
Gene/Protein/Region Type	S

Literature Information

PubMed PMID	10596008
Disease	HBV infection
Published Year	2000
Journal	Journal of medical virology
Title	Effect of variation in the common "a" determinant on the antigenicity of hepatitis B surface antigen.
Author	Seddigh-Tonekaboni S,Waters JA,Jeffers S,Gehrke R,Ofenloch B,Horsch A,Hess G,Thomas HC,Karayiannis P
Evidence	The variant P142S/G145R was also not bound by themonoclonal antibodies or the AUSRIA II assay even ata concentration of 310 ng/ml but the protein containinga change of proline for serine at amino acid 142 alonewas detectable using all of the monoclonal antibodies

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation