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Mutation Information
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Mutation Site
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S16A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
Tat |
Literature Information
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PubMed PMID
|
17083724
|
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Published Year
|
2006 |
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Journal
|
Retrovirology |
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Title
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Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription. |
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Author
|
Ammosova T,Berro R,Jerebtsova M,Jackson A,Charles S,Klase Z,Southerland W,Gordeuk VR,Kashanchi F,Nekhai S |
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Evidence
|
While we could detect phosphorylation of WT Tat (Fig. 8C, lane 2), the Tat S16A mutant and Tat S46A mutant were about 2-3 fold less phosphorylated (Fig. 8C, middle and lower panels, lanes 3 and 4).
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HIV Mutation Detail Information