|
Mutation Information
|
Mutation Site
|
S181P |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
C |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
X72702.1;
X70185.1;
X01587;
GQ377616;
D23682;
D23680;
D16667;
D12980;
AY247032;
AY247030;
AY123041;
AF286594;
AF223957;
AF068756;
AB100695;
AB074755;
AB031262 |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
23071796
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2012 |
|
Journal
|
PloS one |
|
Title
|
Naturally occurring precore/core region mutations of hepatitis B virus genotype C related to hepatocellular carcinoma. |
|
Author
|
Kim DW,Lee SA,Hwang ES,Kook YH,Kim BJ |
|
Evidence
|
Six (preC-W28*, C-P5H/L/T, C-E83D, C-I97F/L, C-L100I and C-Q182K/*) and seven types (preC-W28*, preC-G29D, C-D32N/H, C-E43K, C-P50A/H/Y, C-A131G/N/P and C-S181H/P) of mutations in the preC/C region were found to be related to HCC and to affect the HBeAg serostatus, respectively.
|
|
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HBV Mutation Detail Information