|
Mutation Information
|
Mutation Site
|
S204R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
D |
Literature Information
|
PubMed PMID
|
11481624
|
|
Disease
|
Fulminant hepatitis B
|
|
Published Year
|
2001 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis. |
|
Author
|
Kalinina T,Riu A,Fischer L,Will H,Sterneck M |
|
Evidence
|
Thelowest HBsAg level (approximately 30% of WT) was foundwith mutant M5, which differs from WT by the 3 c-terminallylocated mutations G145R, S204R, and L205V
|
|
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